Crossing beacons

Insect beacons

the applications, thereby delaying the start of this important research. Willis said: " This is a test of the government's commitment to science. Scientists, funders, the regulator and patient interest groups, even the DTI and the prime minister, have spoken out against the Department of Health's proposals. We very much hope that the department will listen and reflect the committee's conclusion...

Inventing Molecular Beacons

Tripartite molecular beacons.

Molecular beacons (MBs) are hairpin-like fluorescent DNA probes that have single-mismatch detection capability. Although they are extremely useful for many solution-based nucleic acid detections, MBs are expensive probes for applications that require the use of a large number of different DNA probes due to the high cost and tedious procedures associated with probe synthesis and purification. In...

Catalytic molecular beacons.

We have constructed catalytic molecular beacons from a hammerhead-type deoxyribozyme by a modular design. The deoxyribozyme was engineered to contain a molecular beacon stem-loop module that, when closed, inhibits the deoxyribozyme module and is complementary to a target oligonucleotide. Binding of target oligonucleotides opens the beacon stem-loop and allosterically activates the deoxyribozyme...

Crossing technique in cowpeas